Neural Correlates, Self-Inquiry, and the Ontology of Healing in Gurmat Therapy
- Gurmat Therapy | Sonya Sanghera

- Sep 30, 2024
- 4 min read
Updated: Apr 25
This article critically explores the emerging interface between neuroscience, contemplative science, and spiritually informed care, focusing on Gurmat Therapy as a psycho-spiritual system rooted in the ontology of Sikh wisdom. While biomedical science offers epistemological insight into neural correlates and biomarkers of spirituality, Gurmat provides an ontological framework for understanding human suffering and transformation.
We argue that self-inquiry (vichaar), disidentification from mental content (man da roop), and the cultivation of Gurmat Aatm Bodh (self-realisation through divine wisdom) are essential for sustainable healing. Drawing on Gurbani, we examine how entanglement with the mind's content activates autonomic nervous system (ANS) dysregulation, perpetuating symptoms of depression and anxiety. Gurmat Therapy, rather than reducing spirituality to neurochemical processes, calls for a reorientation of consciousness from manmukh (egoic identification) to gurmukh (truth-oriented living), initiating a psychophysiological and existential shift toward inner sovereignty.
Gurmat as Ontology, Biomedicine as Epistemology
Contemporary neuroscience attempts to understand spirituality through an epistemological lens; by measuring neural activations, neurotransmitter fluctuations, and biological markers. While this scientific mapping contributes to our knowledge, it does not answer ontological questions: What is the self? What is the root of suffering? From a Gurmat perspective, these are not peripheral inquiries but foundational.
Gurmat begins with the assertion:"Man jeete jag jeet"" One who conquers the mind, conquers the world."– Guru Nanak Sahib, SGGS Ang 6
This reveals an ontological stance, mind is not simply a cognitive organ but a gateway to liberation or bondage. The biomedical model, grounded in material epistemology, seeks explanation through observable phenomena. In contrast, Gurmat is a wisdom-based system of consciousness that sees health as the alignment with truth (Sat), not merely the absence of symptoms.
The Role of Self-Inquiry in Recognising Dysfunction
Self-inquiry (vichaar) is central to Gurmat Therapy. It enables one to become aware of the mind's entanglement with mental content; stories, judgments, and reactive patterns that trigger dysregulation in the nervous system.
Gurbani asserts:"Mann ka rog bade dukh dehi" "The disease of the mind causes great suffering to the body."– Guru Arjan Sahib, SGGS Ang 706
This highlights the intimate link between thought, perception, and physiological dysfunction. The manmukh, one who follows the dictates of the untamed mind, becomes trapped in the stories of the self, activating the stress response and leading to symptoms such as depression, anxiety, chronic fatigue, and dis-ease.
Mind-Body Connection and ANS Dysregulation
Contemporary neuroscience supports what Gurmat has long asserted: entanglement with egoic thought patterns activates the sympathetic branch of the autonomic nervous system (ANS), triggering hyperarousal (anxiety, panic) or hypoarousal (depression, fatigue).
When one becomes entangled with thought, as Gurbani warns:"Eh man rogī thīā rogī bādhā jān""This mind has become diseased, entangled in worldly attachments."– Guru Nanak Sahib, SGGS Ang 415
This entanglement creates a loop between cognitive stress and physiological inflammation. Studies in psychoneuroimmunology confirm that chronic stress disrupts immune function and alters neurochemistry (Davidson et al., 2003; Black & Slavich, 2016). Yet, Gurmat offers not just diagnosis but liberation through spiritual alignment.
From Manmukh to Gurmukh: Repatterning Through Conscious Orientation
The movement from manmukh to gurmukh represents a psycho-spiritual transition and shift in consciousness: from reactive, ego-based identification to divine-centered consciousness. This transformation is not merely ideological, it has embodied, measurable impacts. Practices such as Naam Simran, kirtan, and sehaj dhyan (equipoised awareness) repattern the nervous system by reducing sympathetic arousal, enhancing parasympathetic tone (e.g., via increased HRV), and promoting neuroplasticity.
As Guru Amar Das affirms:"Har har naam samālīai sabh rog kā aukhadh""The Name of the Lord is the medicine for all diseases."– SGGS Ang 814
Here, Naam is not a placebo or affirmation, but a vibrational medicine that reorganises consciousness, pacifies the mind, and restores homeostasis.
Gurmat Therapy: A Post-Diagnostic, Relational Praxis
Gurmat Therapy resists the over-clinicalisation of the psyche. It does not pathologise the mind but contextualises dysfunction as a disconnection from Naam, a distortion of self-identity, and loss of spiritual sovereignty. Gurmat does not deny biology; rather, it places biology in service of divine awareness. The body becomes a vessel (dehi mandir), not a prison.
As Guru Arjan Sahib sings:"Dehi ko simarahi dev" "Even the gods meditate upon the human body (as a sacred vessel)."– SGGS Ang 1076
Healing, then, is not just regulation of symptoms but remembrance of being (surat da mel naal Sat). Gurmat Therapy uses Shabad Vichaar, embodied practices, and psycho-spiritual inquiry to help the individual disidentify from the mann(mental noise) and root themselves in Gurmat Aatm Bodh, a lived realisation of spiritual truth.
Implications for Mental Health and Spirituality
This ontological-epistemological integration has profound clinical and philosophical implications:
Reframing Diagnosis: What psychiatry calls ‘disorder,’ Gurmat may interpret as spiritual entanglement or maan da rog. This does not invalidate medical categories but expands their meaning.
Embodied Liberation: Interventions that incorporate Naam Simran, rhythmic breath, and Sehaj Samadhi practices may have empirical effects, lowering cortisol, improving HRV, but their true purpose is inner sovereignty (raj jog), not merely homeostasis.
Clinician as Companion: The therapist is not just a diagnostician but a sangat presence, a mirror and witness to the soul's emergence beyond the reactive mind.
Conclusion
While neuroscience continues to explore the neural correlates of spiritual states, Gurmat invites us into an ontological inquiry: Who is the one observing the mind? What is the source of health beyond symptom management? Gurmat Therapy bridges this gap, not by reducing spirit to science, but by illuminating how the human nervous system, when attuned to Naam, becomes a conduit for divine remembrance and radical healing.
This is the basic science of spirit, not merely of the brain, but of being.
Author: Sonya Sanghera
References (Updated with Gurbani & Neuroscience Citations)
Black, D. S., & Slavich, G. M. (2016). Mindfulness meditation and the immune system: a systematic review. Annals of the New York Academy of Sciences, 1373(1), 13–24.
Davidson, R. J., et al. (2003). Alterations in brain and immune function produced by mindfulness meditation. Psychosomatic Medicine, 65(4), 564–570.
Newberg, A., & Waldman, M. R. (2009). How God Changes Your Brain. Ballantine Books.
Siri Guru Granth Sahib Ji (SGGS) — All Gurbani citations from Sri Guru Granth Sahib Ji.
Tang, Y. Y., Hölzel, B. K., & Posner, M. I. (2015). The neuroscience of mindfulness meditation. Nature Reviews Neuroscience, 16(4), 213–225.




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